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Clinical Recognition and Therapeutic Development (1980Present) The shift from biochemical curiosity to clinical intervention accelerated in the 1980s when Dean Jones at Emory University demonstrated that glutathione status could be manipulated therapeutically using N-acetylcysteine (NAC), a precursor that bypasses the rate-limiting step in glutathione synthesis

Chemistry Today's November-December 2025 review of peptide synthesis advances explicitly identified "fully aqueous synthesis" and "integration of artificial intelligence to streamline manufacturing processes" as future directions for the field

Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses

The clinical presentation of diverticulitis depends on the location of the affected diverticulum, the severity of the inflammatory process, and the presence of complications