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Animal-model evidence consistently shows local effects: angiogenesis at the injury site (VEGF upregulation), growth-factor signaling (EGF, FGF), nitric oxide pathway modulation, and accelerated tendon-to-bone interface healing in rat Achilles transection studies

The agency may accept, change, or reject the committees recommendations and may explain timing or implementation conditions

The anti-doping community can help by working with national regulators to address these substances and manage them better

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