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One study showed that GLP-1 protected pancreatic beta cells against glucosamine-induced cytotoxicity through suppressing AMPK activity, and subsequently led to recovery of the phosphorylation levels of P70S6K and S6RP and alleviate glucosamine-induced cell death 36

Faecalibacterium prausnitzii-derived extracellular vesicles alleviate chronic colitis-related intestinal fibrosis by macrophage metabolic reprogramming