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For Systemic Application (via Subcutaneous Injection): A standard protocol for general systemic research often starts at the lower end of this spectrum

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Despite large heterogeneity of studies, it has been reported that gut bacteria composition of CAD patients is different from healthy patients

Accordingly, SARS-CoV-2 infection could inflict direct cytopathic injury to gut epithelia and elicit indirect immune-mediated damage to endothelial cells 252