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The adverse events observed align with the known safety profiles of each class used individually, with no indication of synergistic toxicity

Consequently, end-stage renal disease, heart dysfunction (e.g., hypertrophic cardiomyopathy, cardiac arrhythmias, valvular disease) and cerebrovascular events (e.g., transient ischemic attacks, ischemic strokes) are the major life-threatening disease manifestations [4]

Regardless of possible pathways to treatment, Dang said that symptoms like fluctuating blood sugars, heartburn, bloating, or vomiting should all be reason enough for a patient taking a GLP-1 drug to check in with a medical professional

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