labial melanotic macule causes What Caused These Multiple Hyperpigmented Macules of the Mouth? a Multiple brown macules on

PloS One (2013) 8:e76654

oxidative stress markers such as 4-hydroxynonenal (4-HNE), nitric oxide (NO), nitrite/nitrate (NO2/3), glutathione peroxidase (GPx), thiobarbituric acid-reactive substances (TBAR), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione-S-transferase (GST), total antioxidant capacity (TAC)

Some users supplement strategically, and the guide to supplements to take with tirzepatide covers the most evidence-based options for supporting health during treatment

So, if you want to take a walk on the wild side, you can probably drink one past its expiration date, but it might be best to consume it before then