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These hormones are released in response to food intake, particularly carbohydrates and fats

Benefits of the low-dose initiation strategy: Reduced nausea and vomiting: Gradual exposure allows physiological adaptation Improved treatment adherence: Fewer patients discontinue due to side effects Better patient experience: Manageable symptoms support confidence in therapy Lower hypoglycaemia risk: Gradual glucose-lowering effect, particularly important with concurrent sulfonylureas or insulin Patients should be counselled that mild gastrointestinal symptoms during initiation are common and usually temporary

Medications like semaglutide and bupropion can aid in weight loss, but they work best when paired with healthy eating and regular exercise