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When patients aged 50 years old start triple therapy, event-free survival was estimated to increase by 3.2 years (95% CI 2.14.3 years) for MACE, 3.2 years (95% CI 2.44.0 years) for HHF, and 5.5 years (95% CI 4.06.7 years) for CKD progression compared with that for conventional therapy alone