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But some health experts contend that covering the drugs could eliminate the downstream costs involved with treating obesity-related conditions
A network meta-analysis of 22 RCTs covering 2,258 participants found GLP-1 receptor agonists reduced lean mass by a mean of 0.86 kg, with lean mass comprising roughly 25% of total weight lost across agents
They also show how simulations by USC and others based on clinical trial data with its commiserate exclusions of more complex patients can be entirely off base (or why insurers may limit the populations for an indication)
The combined effect is sustainable and safe weight loss for people who take a GLP-1 agonist medication under medical supervision, according to a clinical review of GLP-1 receptor agonists published in Drugs in Context
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