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G s Nanobit complementation assays HEK293AWT cells stably expressing the hGLP-1R were transiently transfected with G -LgBIT, G 1, G 2-SmBIT (1:5:5) 48 h before the assays using standard PEI transfection protocol

However, further research is needed to confirm that the improvements in systemic inflammation and joint symptoms observed with these therapies are also tied to improvements in joint inflammation.