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~ AlphaMD In recent years, the use of kratom, a tropical tree native to Southeast Asia, has gained attention in the Western world for its potential to alleviate pain, enhance mood, and assist in opioid withdrawal

It's likely to be accompanied by other neurological deficits though, and it's worth remembering that muscle stiffness and pain can be caused by many other things

The LD50 has not been established because lethal doses could not be reached in standard toxicology protocols

HUBERMAN: And injured capillaries, and then to promote the activity of a given enzyme called ENOS or endothelial nitric oxide synthase, which then causes more blood vasculature to form at the injury site and around the injury site