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Finally, KDs anti-inflammatory actions extend to the modulation of the Akt/GSK-3/CREB signaling pathway, mediated by histone acetylation in the promoter region of the metabotropic glutamate receptor 5 (mGluR5) in a rat model of PD [44]

For skin-specific concerns, it is best to consult a healthcare provider or dermatologist to determine the appropriate treatment