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Similar to the amphetamines, phentermine increases the release of norepinephrine and dopamine from nerve terminals and inhibits their reuptake

[22] Jiang, Y., Huang, Y., Wu, Y., & Wang, L

You need a consistent calorie deficit and enough training stimulus to protect muscle, but you also need the plan to be repeatable when motivation is not perfect

For instance, when you're short on sleep, you have higher levels of the hormone ghrelin, which is responsible for hunger, and lower levels of the hormone leptin, which is responsible for satiety, or fullness