In fact, twin studies suggest that the heritability of obesity ranges from 70-80%, a number that is only exceeded by height, and far greater than most diseases that are generally accepted to be genetic (like Type-1 diabetes)
Many healthcare professionals recommend combining GLP-1 medications with adequate protein intake and regular strength-training exercises to help preserve muscle mass during weight loss
Variants like GLP1R rs6923761 and FTO rs9939609 may influence metabolic inflammation severity and response patterns, but genetics are one piece of a much larger clinical picture that includes disease activity, antibody status, and functional capacity
*Correspondence: Theerthankar Das, [email protected] Present address: Theerthankar Das, Microbiology and Infectious Diseases, School of Medicine, Ingham Institute, Western Sydney University, NSW, Australia These authors share last authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
