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If thats the case for you, rotate through different sites on your stomach and left and right arms

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Some patients find that administering the injection in the evening allows them to sleep through periods of nausea

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The largest individual exposures in this window include: Mercks pembrolizumab (Keytruda), with $25 billion in 2023 revenue, faces composition of matter patent expiry in 2028, though secondary patents on specific dosing methods, combination regimens, and PD-1 binding domains extend the formal portfolio timeline

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Following the gradual dose escalation schedule helps minimise these effects

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