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Female patients must strictly avoid pregnancy, use dual forms of reliable contraception, and complete mandatory regular pregnancy tests before and during treatment
EDS can also be the result of a spontaneous change or de novo mutation (also called a variant) of your genes
Holzbach RT (1990) Nucleation of cholesterol crystals in native bile
While EAE models have offered valuable insight into adaptive immune responses, demyelination, and axonal damage in MS, they fall short in replicating the full spectrum of human MS pathology, particularly the disease's onset and heterogeneity (Figure 5)
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