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It also reduces the risk of heart problems

The article says animal and human data show that gradual reduction instead allows metabolic re-adaptation and lets appetite-regulation circuits normalize

Two widely used weight loss drugs could significantly reduce the risk of complications in people with the most common type of heart failure A new study reported that semaglutide and tirzepatide effectively lowered the risk of being hospitalized for The findings show that semaglutide, commonly sold under the brand names Ozempic, Wegovy, and Rybelsus, produced similar benefits to those produced by tirzepatide, commonly sold under the brand names Zepbound and Mounjaro

Brazilian Journal of Medical and Biological Research