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Notably, they observed that 1 mmol/L of L-carnitine was more effective than 3 mmol/L, suggesting that higher concentrations may exert nonselective cytotoxic effects, leading to increased Ca 2 influx and less reduction in cell volumetric contraction (Lucius et al., 2023)

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DMT, divalent metal ion transporter

Carnitine also has an anti-inflammatory effect as the integration of diet with LC decreases the anti-proliferative effect induced by the presence of interleukins such as TNF- and its detrimental action reducing the consumption of glucose of the embryo in its early development [98] and reducing growth of the inner cell mass and trophoectoderm in the blastocyst, which leads to delayed embryonic development and reduction of vitality of the embryo [99, 100]