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About one in six children and adolescents, ages 2 to 19, are overweight, according to data from the National Institute of Diabetes and Digestive and Kidney Diseases, and almost one in five children and adolescents in that same age group are categorized as obese

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Some pharmacokinetic studies have examined the lower end of the dose-response curve, but these were conducted to establish appropriate starting doses for titration, not to validate microdosing as a standalone strategy