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In age-standardised numbers, the global prevalence was 831 individuals per 100.000 people ( As outlined earlier, cardiometabolic diseases or risk factors such as type 2 diabetes (Nichols et al., 2004), obesity (Powell-Wiley et al., 2021) and hypertension (Oh and Cho, 2020) are major predictors for HF

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CBF measurements in the prefrontal and limbic ROIs in the cross-sectional clinical study were obtained using ASL perfusion MRI