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How Do I Know It Worked

Here is what 48 weeks of treatment produced: ### Weight Loss by Dose - **1mg weekly:** ~8% body weight loss (initiation dose, sub-therapeutic) - **4mg weekly:** ~17% loss -- comparable to maximum-dose semaglutide - **8mg weekly:** ~22% loss -- comparable to maximum-dose tirzepatide - **12mg weekly:** ~24.2% loss -- the highest ever recorded in any obesity drug trial ### What 24% Loss Looks Like in Practice | Starting Weight | 24% Loss | New Weight | |----------------|----------|------------| | 200 lbs | 48 lbs | 152 lbs | | 250 lbs | 60 lbs | 190 lbs | | 300 lbs | 72 lbs | 228 lbs | | 350 lbs | 84 lbs | 266 lbs | Perhaps most striking: over 50% of participants on the 12mg dose lost 25% or more of their body weight, and the weight loss trajectory was still declining at week 48

Toxicity of vitamin B6 is becoming more common with the symptoms being painful and the cause is typically due to accidentally overdosing via self-prescribing supplements

Some feel fatigued initially others feel energized