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Fat-selective weight loss would be an additional advantage, as the STEP-1 (NCT03548935) trial demonstrated that once-weekly semaglutide 2.4 mg resulted in 3.4 kg (7.5 lb) more loss in lean body mass compared to placebo

For the scientific community, the future involves: Continued Retatrutide Trials: Monitoring the outcomes of Retatrutide's Phase 3 clinical trials to understand its full efficacy and safety profile as a monotherapy

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general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively