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B12 deficiency can cause certain dermatologic issues, including hyperpigmentation and nail discolouration, cracked lips as well as hair changes

Pickart and Thaler isolated it from human serum in 1973 and characterized it as a tripeptide that prolongs survival of normal liver cells and stimulates growth in neoplastic liver tissue 17

In addition, genome editing is an approach in which a specific target gene can be engineered by adding, deleting or replacing the nucleotides

Finally, one trial in 239 participants already suffering from chemotherapy-induced peripheral neuropathy reported a reduction in the severity of neuropathic symptoms with ALCAR (3 g/day for eight weeks) compared to placebo (93)