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Gene expression Selected genes were examined: (i) genes related to mitochondrial uncoupling ( UCP1, UCP2 ), (ii) the gene encoding transmembrane protein fibronectin type III domain-containing protein 5 precursor of irisin ( FNDC5 ), and (iii) the gene involved in NAD + synthesis ( NAMPT ) (Figure 4)

Being deficient in one or more nutrients can negatively affect thyroid health and increase your risk of thyroid disease (7Trusted Source, 8Trusted Source, 9Trusted Source, 10Trusted Source)

Nevertheless, despite extensive research efforts, critical gaps remain regarding strain-specific mechanisms, optimal dosages, long-term safety, and interactions among probiotics, host genetics, and dietary factors

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