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253-258 A meta-analysis conducted in 2023 examined 19 randomized controlled trials including 999 participants and found that various garlic preparations significantly reduced triglycerides, total cholesterol, and LDL cholesterol compared with placebo

NAC may help by supporting antioxidant defenses and reducing oxidative stress, though its effects vary depending on the population and fertility issue being studied.32 In men, one randomized trial found that 600mg of NAC, selenium, or the combination improved semen parameters, with the combination producing stronger effects than either ingredient alone.23 In women undergoing assisted reproduction, NAC has also been studied for oocyte and embryo quality, though this research is still relatively early and not definitive.24 PCOS NAC has attracted particular interest in PCOS, where insulin resistance, inflammation, and oxidative stress often overlap.17 Researchers think NAC may help by improving insulin sensitivity and reducing oxidative stress, which may, in turn, support ovulation and reproductive function

Iacobellis and Villasante Fricke, 2020

Long-term effects of semaglutide on diabetic retinopathy in subjects with type 2 diabetes