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Integration also amplifies the challenges of reproductive cohorts: high dimensionality under modest n, partially missing omics blocks (cycle cancellation, biopsy selection, embryo availability), center/protocol batch structure, and heterogeneous endpoints (biochemical pregnancy vs live birth vs cumulative live birth)

Your provider recommends the one, or the combination, that fits what you need at your visit

Reconstitution B: 80 mg vial + 3 mL BAC water (26.7 mg/mL total) more BAC water for larger, easier-to-measure draws

Methyl Group Transfer: Enzymes add a methyl group to methionine, forming SAMe, which donates the group to DNA, RNA, and proteins, turning into SAH