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Ensure adequate protein intake: Aim for 1.2 to 1.6g of protein per kilogram of body weight daily to preserve lean muscle mass during weight loss

Zhou Q, Zhang MM, Liu M et al (2021) LncRNA XIST sponges miR-199a-3p to modulate the Sp1/LRRK2 signal pathway to accelerate Parkinsons disease progression

This typically involves providing evidence of obesity-related health issues, such as diabetes, hypertension, or sleep apnea, and demonstrating that non-surgical interventions have been unsuccessful

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