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Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%

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This is consistent with the excellent safety profile of copper peptides documented across multiple studies, and is a significant advantage over pharmaceutical treatments like minoxidil (which commonly causes scalp irritation) and finasteride (which carries risk of sexual side effects)

However, unlike pro-fibrotic agents, GHK-Cu also upregulates the activity of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), facilitating the breakdown of scarred or disorganized collagen