Estrogen or more precisely, the lack of it during menopause, when the ovaries dramatically reduce their output may impact how GLP-1s work
Protect Your Metabolism While Losing Weight When you go on a diet, you dont just lose fat you lose muscle too Losing muscle is a problem because muscle burns more calories than fat, and even burns calories when you are at rest. Harvard Health explains that muscle mass is one of the strongest determinants of basal metabolic rate (BMR), meaning the more muscle mass you have, the higher your BMR will generally be. Separately, Cleveland Clinic notes that cutting calories too drastically, especially protein, can lead the body to break down muscle for fuel, and it emphasizes that muscle mass plays an important role in keeping your metabolism powered up. John Peel explains it clearly in his GLP-1 support strength series: The goal is not just watching the scale move
Diabetes, Obesity & Metabolism
Women are more likely than men to seek medical care for weight-related concerns, to discuss body-weight changes with clinicians, and to pursue pharmacological options when lifestyle interventions fail
