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A report published last year from KFF, a nonprofit group that researches health policy issues, found that in 2021, people with employer-based health insurance who were overweight or had obesity had an average of $12,588 in total annual health costs, more than double the $4,699 in health spending for those who werent overweight or didnt have obesity

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Accordingly, pharmacological inhibition of SLC7A11 or cysteine deprivation blocks GSH synthesis, leads to GSH depletion, and induces ferroptosis by disabling the antioxidant defense system 85,137