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Firstly, there is an urgent need for extended follow-up studies that last longer than current trial lengths to assess the long-term safety and efficacy of therapies over a decade or more
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safer alternatives (oral/topical glutathione, dermatologic/lightening creams or treatments) are preferable
These therapies can help restore moisture and improve the thickness and elasticity of vaginal tissues, which may be affected if your estrogen levels have dropped due to significant fat loss
Higher-dose oral contraceptives (rarely prescribed today) provide slightly larger hormone margins and may offer theoretical advantage, but most modern pills use lower doses for safety
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