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Human data are limited

The best candidates are people who are already at or near their goal weight but have specific areas that won't respond to diet and exercise

Ranging from serious (medical) to minor (diet), these absorption and storage issues stem from a variety of reasons

Of note, the relative abundance of the Parasutterella genus, which was significantly enriched in both the vehicle- and 5A-1MQ-treated animals transitioned from WD to LD compared to both the WD and LD control groups, was observed to be significantly correlated (either positively or negatively) with 30 EWAT metabolites, both with and without outliers included