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(Article in Japanese) Mutomba MC, Yuan H, Konyavko M, et al

For ligament work, the canonical reference is Cerovecki and colleagues 2010 study of medial collateral ligament transection in rats, in which intraperitoneal, oral (drinking water), and topical BPC-157 administration each produced consistent improvements in functional, biomechanical, macroscopic, and histological healing endpoints over a 90-day window (Cerovecki et al., 2010)

The mPTP is a multi-protein complex that, when persistently open, causes mitochondrial swelling, potentially leading to rupture of the mitochondrial outer membrane

Several factors may contribute to this change