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CD38 hydrolyzes NAD+ into nicotinamide and ADP-ribose, directly reducing the pool of NAD+ available for sirtuins and PARP-1

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You need it for normal biological and physiological processes like: Biosynthesis of DNA Healthy red blood cells Maintenance of the gut mucosa and skin cells Metabolism of fat, protein, and carbohydrates Folate metabolism and the folate pathway Formation of choline-containing phospholipids Formation of succinyl coenzyme A which is needed for neural lipids and myelination Maintenance of the myelin sheath that surrounds neurons and protects against nerve damage Healthy energy levels Most water-soluble vitamins are not stored in the body and must be regularly replenished