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Key medications that slow CKD progression: ACE inhibitors & ARBs cornerstone therapy to reduce proteinuria and protect kidney function SGLT2 inhibitors originally for diabetes, now proven to reduce CKD progression and hospitalizations for heart failure GLP-1 receptor agonists improve glycemic control and show cardiovascular and kidney benefits Non-steroidal MRAs (finerenone) a new option to reduce albuminuria and improve outcomes in diabetic CKD These therapies, when used together and tailored to the patient, represent a modern stack of treatments that can delay or even prevent kidney failure

doi: 10.1126/science.1104742

Compassion B

By improving fat transport, the medicine may help your muscles use fat instead of sugar, which can improve endurance and may support gradual fat loss when combined with diet and exercise