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This inhibition is due to the activation of -adrenoceptors on the -cell membrane, which results in a decrease in intracellular levels of cAMP
Thomas JD, Dattani A, Zemrak F, Burchell T, Akker SA, Gurnell M, et al
Well-formulated 2% products often outperform poorly formulated 4% products
10.1038/s41598-018-33385-z Summary Keywords nitazoxanide, methotrexate, hepatotoxicity, endoplasmic reticulum stress, rat Citation Mahmoud NM, Elshazly SM, El-shaarawy F, Zaitone SA, Aldahish AA, Ahmed GA, Fawzy MS, Aloyouni SY, Abed SY, Saeedi T and El-Sayed SS (2024) Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
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