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You should contact a doctor or seek emergency care if you experience: Difficulty breathing or swallowing Significant facial or throat swelling Persistent or worsening injection-site reactions (such as increasing pain, pus, or red streaks) Severe, unusual, or unexpected symptoms after use Signs of systemic illness like extreme fatigue, jaundice (yellowing of the skin or eyes), or neurological changes, which could indicate severe copper imbalance
39-41 For example, a particular increase in SOCS3 expression is observed in ARC neurons of mice with diet-induced obesity and this may be a key cause of leptin resistance
doi: 10.3389/fimmu.2018.02484 250 PelfreyCMCotleurACLeeJCRudickRA
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