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It is also consistent with a small clinical trial study of the GLP-1RA drug exenatide, which significantly reduced heavy drinking days and total alcohol intake in patients with obesity 12 and with a register-based study in Demark showing that GLP-1RAs (though semaglutide was not included) compared with dipeptidyl peptidase 4 inhibitors (DPP4) were associated with lower incidence of alcohol-related events in 20092017 13

This leads to compulsive patterns of use or behavior

Hydration Authority Says: If you're sweating heavily or eating very low-carb on GLP-1s, LMNT might be exactly what your body needs

Without sufficient magnesium to regulate nerve impulses, the sympathetic nervous system fires unchecked, creating a vicious cycle of stress, nutrient depletion, and worsening autonomic dysfunction