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Melatonin and sorafenib together induce apoptosis through the activation of JNK/c-jun and repress the protective autophagy induced by sorafenib in HCC cells

Purification is typically performed using high-performance liquid chromatography, and analytical verification methods such as mass spectrometry are used to confirm peptide identity

Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism