glp-1 mrna Enhancing expression via IVT and fusion protein technology for diabetes therapy The Multifaceted Nature of GLP-1:

We knew from previous research that being overweight and having excess body fat is a recognized risk factor for insulin resistance and type 2 diabetes, which complicate cancer therapy, says Thomas George, MD, a professor of medicine and interim director of the University of Florida Health Cancer Institute in Gainesville and one of the study authors

J.et al (2009)

However, for patients with very high blood sugar at diagnosis (HbA1c above 10 percent) or symptoms of hyperglycemia, insulin may be started right away, bypassing the usual stepwise approach

By day 5, 6, and 7, semaglutide levels are declining but still therapeutic