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Injection Site Reactions: A mild local reaction at the injection site can occasionally occur and usually clears up on its own without any treatment needed

Moreover, Nataraja and Bright showed that curcumin inhibited EAE decreasing IL-12 production from macrophage/microglial cells, and by inhibition of IL-12-induced tyrosine phosphorylation of Janus kinase 2 (JAK2), tyrosine kinase (TYK2), and STAT 3 and STAT4 transcription factors leads a decrease of T cell proliferation and Th1 differentiation (Natarajan and Bright, 2002)

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