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Hair follicles are among the most metabolically active structures in the human body

doi: 10.1017/S000711451200565X

The increasing number of studies that are focused on TXN, TXNRD1, and TXNIP for the purpose of cancer therapy has further demonstrated the importance of the Trx system in the development of cancer Several studies have shown that the disruption of the Trx system can lead to increased oxidative stress, inflammation, and apoptosis, which are all associated with cancer progression

This microglial clearance impairment may result from reprogramming microglial function from a homeostatic, phagocytic state to a pro-inflammatory phenotype, which further worsens AD pathology