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Consider Alternative Strategies For some patients, the following approaches may be discussed: Extended treatment duration : Continuing Wegovy beyond the initial assessment period, within the 2-year maximum treatment duration Intensified lifestyle intervention : Additional support within specialist weight management services Alternative medications : If Wegovy proves ineffective, other UK-licensed options such as orlistat or naltrexone/bupropion may be considered (availability varies by local NHS commissioning policies) Bariatric surgery referral : For individuals with BMI 40 kg/m (or 35 kg/m with comorbidities) who have not responded to non-surgical approaches

There also have been no clinical trials to see if Rybelsus is safe or effective for people under the age of 18 (Novo Nordisk, 2021)

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