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Immune modulation Explored as a tuftsin analog for immunomodulatory activity, largely in animal and cell-based preclinical studies

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The accurate characterization of MK-677 is: an investigational small-molecule ghrelin-receptor agonist that reached Phase II human trials in several indications, never obtained FDA approval, and whose clinical development was discontinued

Environ Res 214:114202 Wu ZB, Gatesoupe FJ, Li TT, Wang XH, Zhang QQ, Feng DY, Feng YQ, Chen H, Li AH (2018) Significant improvement of intestinal microbiota of gibel carp ( Carassius auratus gibelio) after traditional Chinese medicine feeding