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Nevertheless, neurons can detoxify H 2 O 2 , but apparently this capacity is more greater in astrocytes for which they play a putative role in the modulation of the neurotoxic effects of H 2 O 2 [45, 46, 52]

It is accepted that an excessive burden of ROS may lead to abnormal cell growth, corresponding changes in intracellular homeostasis and damage to important components of in the cell when the antioxidant defense and/or DNA repair mechanisms cannot balance the excess oxidants [29]

Structural characteristics: GHK-Cu supports tight copper chelation while maintaining aqueous solubility and compatibility with biological matrices, enabling reproducible dosing and consistent behavior in in vitro, ex vivo, and in vivo research systems

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