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At minimum: Outcomes Weight trend (weekly average) Waist circumference Body composition if available (DEXA, BIA with consistency) Strength markers (basic lifts, grip strength, functional tests) Safety Blood pressure + resting HR A1c and fasting glucose (more often if diabetes) CMP (liver/kidney) Lipids (periodic) If manipulating GH/IGF-1 signaling: IGF-1 (and clinical context matters) Stop criteria Persistent tachycardia, edema, severe fatigue, worsening glycemia, abnormal labs, or new symptoms you cant explain The what to ask your clinic questions (high signal, low fluff) If a clinic recommends a peptide stack, ask: What is the problem were solving, in one sentence
To maintain optimal glutathione levels, you can rely on your bodys natural production, but it may not be as potent as supplementation
One notable trial in 20 subjects compared the effects of the retinoid tretinoin, which is about 10x more potent than retinol, to the effects of GHK-Cu on dermal procollagen synthesis, epidermal proliferation, and inflammation
For instance, studies have indicated that intravenous (IV) glutathione administration can lead to significant improvements in liver function markers among patients with fatty liver disease
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