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A Spearman correlation analysis confirmed that the pathological index of steatosis was negatively correlated with the hepatic GLP-1R expression level (Fig

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Inclusion Criteria The included studies had to meet the following criteria: Studies that reported the combined use of GLP1-RAs and SGLT2is in individuals with T2D were included if they provided a clear description of the study design and well-defined measurements for any outcome relevant to the research questions

Patients experiencing inadequate response or intolerable side effects should be referred back to their prescribing physician for dose adjustment or consideration of alternative weight management strategies