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If the most uncomfortable period falls within the first four to eight hours after injection, and you inject at 8 PM or 9 PM, then the peak discomfort window aligns with your sleeping hours

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Ann N Y Acad Sci 786:217223 Paolicchi A, Minotti G, Tonarelli P, Tongiani R, De Cesare D, Mezzetti A, Dominici S, Comporti M, Pompella A (1999) Gamma-glutamyltranspeptidase-dependent iron reduction and LDL oxidationa potential mechanism in atherosclerosis

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