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Nature communications 2017;8, 15691, doi:10.1038/ncomms15691
20 These results were consistent in patients regardless of the etiology of their vitamin B 12 deficiency, including malabsorption states and pernicious anemia
While glutamate is essential for normal brain function, an excess of it combined with reduced glutathione levels can cause brain damage
Here, we show that culturing lymphoid cells in 3D gels triggers reactive oxygen species (ROS) production, leading to non-tumor lymphoid cell death while enabling the survival and proliferation of a subset of lymphoma/leukemia cells, TICs or TIC-like cells
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