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FIGURE 6 Transcriptional response to chronic infusion of oIGF-1 in skeletal muscle and liver Liver mRNA expression of IGF-1 was 58% lower in oIGF-1 compared to SAL infused fetuses ( p = 0.01) (Figure 7)

Approach We explore the properties of glutathione metabolism in the liver by experimenting with a mathematical model of one-carbon metabolism, the transsulfuration pathway, and glutathione synthesis, transport, and breakdown